At club level a very popular approach is to set up a particular formation regardless of what the opponent plays. A triangle of pawns on e3, d4 and c3 is one example, and White might also put a pawn on f4 to produce a Stonewall Attack. The fact that this can also be used as Black against 1.d4 and Flank Openings is often seen as a bonus because there’s less to learn. But there are also dark sides.
The main issue is that a variety of formations are needed to cultivate one’s positional understanding, without this players stagnate. There’s also a practical case for not being too predictable; if someone knows what set-up you’re going to adopt he can lay out his own forces so that they adapt.
Here’s a stonewall formation getting taken apart by the then youthful Vlastimil Hort with White never really getting much play. It’s not that White is lost out of the opening, and I’m sure that improvements can be found. It’s just that it’s a serious handicap, which you can well do without when facing powerful opposition.